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Meron Gribetz - Inner Cosmos, Private Partnering Interview at LSI USA '23

Inner Cosmos' digital pill is a subcutaneously implanted brain-computer interface (BCI) to rebalance the brain. The company is initially focused on developing their solution for the treatment of depression.

Transcription


Meron Gribetz  0:06  


My name is Meron Gribetz. I'm the CEO of neuro technology company called Inner Cosmos. The Inner Cosmos technology consists of a tiny Neuro Stimulator for the largest chronic disorder on the planet, depression, it gets slipped under the skin over the prefrontal cortex, behind the hairline on the left, and a 30 minute outpatient procedure. That's very quick. And for the rest of your life, your depression is essentially manage on your phone. And it's a much more modern pharmaceutical industry. Technology. Current forms of nerve stimulation consists of electric shock therapy, which is 100 year old technology that creates a seizure in the brain, transcranial magnetic stimulation, which is a more modern version of that about 30 years old. It's a more focal stimulation, it has less side effects, but it has a much higher compliance problem, you have to see the doctor 20 days in a row, which for a depressed patient that can often not really motivate themselves to get into bed is a tall order. So what we've done is we've created TMS transcranial magnetic stimulation to go, that large refrigerator size machine is now the size of a penny. And it's with you for life, solving the compliance problem, creating a much more modern depression solution. Our technology fundamentally is a huge disrupter for the psychiatric for the psychiatry industry. Because right now, as a patient, I have to go to the doctor, take the day off, get a piece of paper, go to CVS, get a drug that's going to make 50% of patients or more in the case of antidepressants, male patients lose their libido, mental fog fatigue suicidality, when I switch cocktails, and I'll have to wait six weeks before I'll know if it works. And then I'll probably have to do this whole thing again, it is the most widely used terrible technology on the planet. Compare that with 30 minute outpatient procedure, I go to the doctor once and for the rest of my life, my doctor can remotely send me the most latest prescription from the FDA just downloaded it to my device like a Tesla would get the self driving car algorithm download to their device, and I can be remotely managed. This can save the healthcare industry billions and billions of dollars, and completely change the way we do psychiatry. And most importantly, the user experience for the patient is second to none. The inner Cosmos devices a platform play. Our first indication is depression. But we are targeting all the mass market cognitive disorders that you can think of anxiety, bipolar, ADHD, and more. This is the inner Cosmos device very much like a pair of air pods. I'll explain how it works in just a moment. So inside here, you'll see two things. One of them is what the patient will never see because it's embedded. This has slipped under their skin and a 30 minute outpatient procedure. It's one of the tiniest brain computer interfaces in the world for the largest chronic disorder of depression. What do you have here is a major disrupter in the psychiatry industry. This will be the standard of care after pharmaceuticals. How does it work? It magnetically couples for 30 minutes a day, on the hair of the patient just for 2020 30 minutes when they're having a coffee. And it gets all the latest algorithms from the cloud, AKA your latest prescription from your psychiatrist. And it also records the data from your depression levels, sends them up to the cloud and to your psychiatrist. So in the future, you'll never have to get a prescription again, it all gets downloaded automatically to your prescription pod. And then you can charge it in the charging case, you can have a few of them, for example, and each one will have about two days worth of juice. As I said for 30 minutes a day or less. It will be magnetically coupled on the hair. The patient will open the app, they'll see their mood graph their depression graph, which has never been done before and any medical device accurately. They'll see their therapy streak the next therapy session going to the next tab, they'll be able to connect the app to the implant using the connection tool. So you can now see that it's connected, and you can actually see and feel a pattern of connection. And then you'll get your digital prescription, which will include how many days what the expiration how many more doses you have all digital. And finally, you'll be able to start your therapy by swiping it and then you can see the therapy is beginning and it's going through the motion. And at the end, you can stop your therapy. That's pretty much it then you can talk to your doctor remotely. And there are even some apps that you can download that can help support your therapy in more powerful ways. I'll get to that another time. But fundamentally, this is the future of psychiatry. There's no way We're going to use this 100 year old technology in the future, I believe. And we're trying to create something that's super easy to use and exciting for patients and for doctors. So the history of this device begins with a very large and complicated computer that has some very, very high features, it's able to sense at really high resolution through the bone through the skull, so you don't have to penetrate the skull, like, like every other brain computer interface. And then we took this and we miniaturize it to the size of a half a thumbnail. That's our ASIC over there for most companies that cost about 100 or $200 million to take it from this to this. And we were able to do that in the last few years. This all gets miniaturized into our digital pill and our Power Pod, which you can see over here is and you might have different prescriptions for different indications that go into that charger. And then of course, the digital pill is embedded under the skin communicating wirelessly with the Power Pod. And that's a bit That's the history of our device. We think in the future this can be next step for psychiatric industry and and how people consume prescriptions. I'm a good friend of of Henry's and Scott's and they were gracious enough to invite us here to LSI to meet with top tier investors, partners, and yeah, just a wonderful place for medical technology companies to come together and build this family.


 

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