As we kick off 2025, strategic planning is at the forefront for companies across the medtech industry. Corporate leaders, investors, and innovators are all asking: Which medtech segments are growing the fastest, and how can we position ourselves to capitalize on these emerging opportunities?
In this edition, we examine the five fastest-growing medtech segments that are poised to dominate in 2025 based on the latest trends and data:
Let’s dive into the driving forces behind these rapidly expanding markets.
The market for pulsed-field ablation devices is experiencing explosive growth as this technology transforms the way atrial fibrillation (AFib) is treated. AFib affects over 60 million people globally, and PFA devices offer a safer, more effective treatment compared to conventional thermal methods, like radiofrequency and cryoablation.
PFA uses precisely controlled electrical pulses to target heart tissue, selectively ablate it, and preserve surrounding structures. This technology has been praised for its reduced complication rates and promising long-term results, making it a favorite among both healthcare providers and patients.
As the adoption of PFA devices grows, the market is projected to experience an impressive compound annual growth rate (CAGR) of 80.7% between 2023 and 2028. The recent U.S. release of PFA systems, such as Farapulse from Boston Scientific and Pulseselect from Medtronic, marks a pivotal milestone. Notably, Boston Scientific’s Advent trial demonstrated key safety and efficacy benefits over other ablation methods.
The potential of PFA extends beyond cardiovascular applications—researchers are also exploring its use for diabetes, cancer, and respiratory conditions, adding to its broad market appeal.
Intravascular lithotripsy has become a game-changer for patients suffering from heavily calcified vascular lesions, particularly in coronary and peripheral artery diseases. This technique uses sound waves to fracture calcified plaques, making it easier and safer to place stents.
The growing prevalence of cardiovascular disease, particularly in aging populations, has created significant demand for IVL technology. This method reduces complications and improves procedure success rates, contributing to the rapid expansion of the revascularization devices market.
LSI’s Market Intelligence team forecasts that the IVL market will grow at a CAGR of 23.6% from 2023 to 2028. The technology is set to disrupt the conventional atherectomy market, with IVL now emerging as a preferred option for treating calcified lesions. With over 6 million coronary interventions and 1.5 million eligible peripheral angioplasties performed annually, the potential for IVL is vast.
In 2024, Johnson & Johnson acquired Shockwave Medical for approximately $13 billion, further solidifying its position in one of the fastest-growing medtech segments.
Transcatheter mitral valve repair replacement devices are revolutionizing the treatment of mitral regurgitation (MR), providing a minimally invasive alternative to traditional open-heart surgery. This innovation reduces recovery times and procedural risks, making it an increasingly viable option for a wider range of patients.
Mitral valve disease impacts over 24 million people globally—a much larger patient population compared to aortic valve disease. As awareness grows and more patients become eligible for treatment, the market for transcatheter mitral valve devices is booming. The market is expected to grow at a CAGR of 23.3%, reshaping structural heart care.
The demand for these devices is underscored by the growing number of patients with MR, many of whom previously had limited treatment options. Edwards Lifesciences, which invested heavily in this space, continues to expand its footprint with the acquisition of Innovalve for $300 million.
In 2023, renal denervation devices gained FDA approval for technologies from ReCor Medical and Medtronic, offering a breakthrough solution for managing drug-resistant hypertension. RDN works by disrupting renal nerve activity, resulting in sustained reductions in blood pressure.
Hypertension affects over 1.3 billion people globally, with many struggling to manage it through medication alone. As a result, RDN devices are expected to see a surge in demand, with the market projected to grow at a CAGR of 22.0% between 2023 and 2028.
The long-term effectiveness of RDN is still being explored, but new clinical data has replaced years of skepticism with growing confidence in the technology. This market is primed for continued growth as the global population increasingly seeks non-pharmaceutical solutions for hypertension.
Transcatheter pulmonary valves provide a life-changing solution for patients with congenital heart disease (CHD), enabling valve replacement without the need for open-heart surgery. This minimally invasive approach is especially critical as more CHD patients live into adulthood, requiring repeat interventions.
The TPV market is expected to grow at a CAGR of 21.9% from 2023 to 2028. Despite fewer than 10,000 annual pulmonary valve procedures, advancements in pediatric cardiology are driving growth in this segment, as TPVs become essential for managing long-term CHD outcomes.
Currently, Edwards Lifesciences and Medtronic dominate this market, but as demand increases, more players are likely to enter the space, although high barriers to entry remain.
2025 marks an exciting era for medtech, with these fastest-growing medtech segments offering transformative solutions to some of the most pressing healthcare challenges. As innovations like Pulsed Field Ablation, Intravascular Lithotripsy, and Renal Denervation continue to advance, the potential to improve patient outcomes and revolutionize treatment options is immense. Keeping an eye on these markets will be essential for stakeholders looking to lead the next wave of healthcare progress.
Want to dive deeper? Join us for our webinar, Medtech Market Outlook for 2025.
Gain access to the latest data and insights driving the medtech industry. Explore our Global Procedure Volumes Database to stay informed on key market trends and make data-driven decisions.
Looking for customized solutions? Reach out to our team of experts to discover how LSI’s Market Intelligence services can help you navigate industry changes and stay ahead of the competition.
Schedule an exploratory call
Request Info© 2025 Life Science Intelligence, Inc., All Rights Reserved. | Privacy Policy
